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Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study

Immunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown. This study investigated whether maternal prebiotic supplementation alters the levels of immunomodulatory proteins in HM. 

Citation:
Divakara N, Dempsey Z, Saraswati C, Garssen J, Silva D, Keelan JA, Christophersen CT, Cooper MN, Prescott SL, Palmer DJ, Verhasselt V, Macchiaverni P. Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study. Pediatr Allergy Immunol. 2024;35(9):e14226.

Keywords:
GOS/FOS; early intervention; human milk; immune regulation; maternal supplementation; prebiotics.

Abstract:
Immunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown. This study investigated whether maternal prebiotic supplementation alters the levels of immunomodulatory proteins in HM.