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Reports and Findings

Sialic acid-to-urea ratio as a measure of airway surface hydration

We explored a robust method to estimate mucus hydration using sialic acid as a marker for mucin content.

Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges

Recruitment of large numbers of pediatric pneumonia and meningitis cases and community controls in a third-world setting presents unique challenges

Cord blood Streptococcus pneumoniae-specific cellular immune responses predict early pneumococcal carriage in high-risk infants in Papua New Guinea

We aimed to explore whether newborns in high-risk areas have pre-existing pneumococcal-specific cellular immune responses that effects early acquisition.

Identification and characterization of a dendritic cell precursor in parenchymal lung tissue

This is the first study to describe a pulmonary precursor cell for dendritic cells in lung tissue

Maternal dietary intake in pregnancy and lactation and allergic disease outcomes in offspring

As the prevalence of allergic disease dramatically rises worldwide, prevention strategies are increasingly being considered.

Comparison of outcomes following a cytological or histological diagnosis of malignant mesothelioma

This study examines survival differences between patients with epithelioid MM diagnosed by cytology only and other subtypes diagnosed by histology.

The role of PKCzeta in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil

Here, we present evidence that there are two major control points to explain the immunodeficiency in CB T-cells, leading to a decreased IFNy synthesis.

Chest imaging in cystic fibrosis studies: What counts, and can be counted?

The aim of this study is to characterize the role of currently available CT and MRI markers in clinical studies, and to discuss challenges with CF studies.

Neuroanatomical Predictors of Functional Outcome in Individuals at Ultra-High Risk for Psychosis

The poorest functional outcomes have the lowest grey matter densities at identification as ultra-high risk for psychosis