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Reports and Findings

Humanized CD70-targeted CAR-T cells with reduced fratricide demonstrate potent antitumor activity against AML and RCC

Chimeric antigen receptor (CAR)-T cell therapy has achieved remarkable success in B-cell malignancies, but its application in acute myeloid leukemia (AML) and renal cell carcinoma (RCC) remains challenging due to the lack of ideal target antigens. C…

Associations between maternal nutrition among women with hyperglycaemia in pregnancy and childhood anthropometry: The PANDORA cohort

The aim of this study was to describe the associations of nutrition during pregnancy with childhood anthropometry among First Nations and non-First Nations women with hyperglycaemia in pregnancy.

Maternal RSVpreF Vaccine Effectiveness Against Respiratory Syncytial Virus in Hospitalized Infants

In February 2025, Australia introduced maternal vaccination with bivalent respiratory syncytial virus prefusion F protein-based vaccine (RSVpreF) in the National Immunization Program for pregnant individuals from 28 weeks' gestation as the primary,…

Are Sensory Features a Subdomain of Restricted and Repetitive Behaviors? Evaluating Empirical Support for the DSM-5 Autism Criteria

Following calls to formally recognize sensory differences in the autism diagnostic criteria, the DSM-5 introduced sensory features as a subdomain of restricted and repetitive behaviors. However, this categorization was developed based on expert cons…

Physiological Impacts of Type 1 Diabetes on Exercise Performance: A Systematic Review and Narrative Synthesis of the Literature

Type 1 diabetes may influence acute and adaptive responses to exercise training and performance. This systematic review aimed to summarize the evidence comparing exercise performance between individuals with and without T1D and to identify the physi…

Concurrent Associations Between the OMNI Rating of Perceived Exertion and Measures of Monitoring Training Load in Non-Elite Adolescent Team Sport Athletes

This study aimed to investigate associations between training load (TL) calculated using the OMNI rating of perceived exertion scale (OMNI-RPE) and heart rate (HR) and velocity-derived measures of TL in non-elite adolescent team sport athletes. Fift…

Long Non-Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Asthma affects millions worldwide. Long non-coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma and respiratory illnesses. LncRNA serve important regulatory roles in numerous pathways, especially gene expression.

The Childhood Cancer and Leukemia International Consortium (CLIC): Expanding global collaboration in pediatric cancer etiology research

Childhood cancers are rare, but incidence has risen modestly in countries with robust registration, partly reflecting improved diagnosis. In high-income countries, cancer is the leading cause of disease-related death in children. Marked inequities i…

SARS-CoV-2 Ancestral and Omicron variant immunity in Australian children in 2023, a seroprevalence study

The emergence of the SARS-CoV-2 Omicron variant in late 2021 led to widespread infection in Australian children, many unvaccinated. The breadth and magnitude of antibody responses to SARS-CoV-2 variant infections and vaccination in children remain i…

Cardiovascular health among young adults: Do childhood neighborhoods matter?

We examine the associations between characteristics of young adults’ communities and their cardiovascular health. Young adult cardiovascular health (CVH) is assessed by a set of eight factors encompassing both health-related behaviors and clinical m…