Reports and Findings
Research
Innate immune activation occurs in acute food protein–induced enterocolitis syndrome reactionsFood reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system
Research
Birth seasonality and risk of autism spectrum disorderIn the first multinational study of birth seasonality of autism spectrum disorder, there was evidence supporting the presence of seasonal trends in Finland and Sweden
Research
Role of HLA-DQ typing and anti-tissue transglutaminase antibody titers in diagnosing celiac disease without duodenal biopsy in type 1 diabetesHLA-DQ typing is not cost effective as a first-line screening test for CD in T1D patients because of over-representation of CD permissive HLA alleles in this group
Research
Severity Assessment in CDKL5 Deficiency DisorderA severity assessment was rapidly developed with input from multiple stakeholders. Refinement through ongoing validation is required for future clinical trials.
Research
Challenges to curing primary brain tumoursThe seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours
Research
Antisense Transcription in Loci Associated to Hereditary Neurodegenerative DiseasesEvidence for the existence of additional regulatory mechanisms of the expression of neurodegenerative disease-causing genes by antisense long noncoding RNAs
Research
MicroRNA Signatures in Malignant Pleural Mesothelioma EffusionsThese results suggest that the expression of miR-143, miR-210, and miR-200c in PE cells might provide a signature for diagnosing malignant pleural mesothelioma
Research
High-Rise Apartments and Urban Mental Health—Historical and Contemporary ViewsHigh-rise apartment buildings have long been associated with the poor mental health of their residents
Research
Role of pre-existing adversity and child maltreatment on mental health outcomes for children involved in child protection: population-based data linkage studyYoung people who have been involved in the child protection system are at increased risk for mental health events and diagnoses
Research
Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000-17: a spatial and temporal modelling studyOur study highlights important spatial and temporal patterns in the clinical burden and prevalence of P vivax