Reports and Findings
Research
A phenotype centric benchmark of variant prioritisation toolsWe hypothesised that the performance of variant prioriisation tools may vary by disease phenotype.
Research
Cerebral palsy and genomics: an international consortiumAccumulating evidence of the role of genetic variation in CP aetiology suggests that individuals with CP should undergo genomic testing as part of their diagnostic workup
Research
Dedicated paediatric Outpatient Parenteral Antimicrobial Therapy medical support: a pre-post observational studyWe examined the impact of introducing a dedicated team to OPAT, to define the role of increased medical oversight in improving patient outcomes in this cohort.
Research
The NICE-GUT trial protocol: A randomised, placebo controlled trial of oral nitazoxanide for the empiric treatment of acute gastroenteritis among Australian Aboriginal childrenDiarrhoeal disease is the second leading cause of death in children under 5 years globally, killing 525 000 annually. Australian Aboriginal and Torres Strait Islander (hereafter Aboriginal) children suffer a high burden of disease.
Research
Online interventions for the mental health needs of trans and gender diverse young peopleMembers of our research team have done an online survey (Trans Pathways) exploring the mental health and care pathways of gender diverse youth in Australia.
Research
Oral prednisolone in preschool children with virus-associated wheeze: A prospective, randomised, double-blind, placebo-controlled trialPreschool children often have episodes of virus-associated wheeze and assessing efficacy of corticosteroids for paediatric wheeze exacerbations is inconcludsive
Research
Sustained participation in annual continuous quality improvement activities improves quality of care for Aboriginal and Torres Strait Islander childrenTo determine whether participation in the CQI Audit and Best Practice for Chronic Disease programme improved care and outcomes for Indigenous children.
Research
School readiness of maltreated children: Associations of timing, type, and chronicity of maltreatmentIn this study, the Australian Early Development Census scores of 19,203 children were linked to information on child maltreatment allegations.
Research
Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in childrenIn this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting children with congenital heart defects (CHD), particularly in the context of multiple subtypes of CHD.
Research
Reduction in hypoglycemia with the predictive low-Glucose management system: A long-term randomized controlled trial in adolescents with type 1 diabetesShort-term studies with automated systems that suspend insulin when hypoglycemia is predicted have shown a reduction, but safety and efficacy aren't established