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Reports and Findings

Expression Levels of Therapeutic Targets as Indicators of Sensitivity to Targeted Therapeutics

We investigated the relationship between the sensitivity of hundreds of cell lines to hundreds of drugs, and the relative expression levels of the targets

A cross-sectional examination of the clinical significance of autistic traits in individuals experiencing a first episode of psychosis

Results suggest that autism traits are associated with poorer clinical presentation in first-episode psychosis populations

Immune-mediated ECM depletion improves tumour perfusion and payload delivery

We have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds

S. aureus colonization in healthy Australian adults receiving an investigational S. aureus 3-antigen vaccine

Based on descriptive analyses of this small study, S. aureus 3-antigen vaccine vaccination did not impact S. aureus acquisition or carriage

Shade coverage, ultraviolet radiation and children’s physical activity in early childhood education and care

The provision of shade, particularly through natural forms such as tree canopy, is an important sun protection strategy and enabler of outdoor time

A Qualitative Exploration of Electronic Image Sharing Among Young People: Navigating the Issues of Conformity, Trust, Intention, and Reputation

This research sought to explore the main factors affecting young people's image-sharing behaviors, particularly in the context of peer relationships and norms

Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial.

Whole genome sequencing of poor and exceptional survivors identified a gain in Chromosome 19 that was exclusive to the exceptional survivors

Personalised analytics for rare disease diagnostics

Here we focus on the problem of prioritising variants with respect to the observed disease phenotype

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2018: the Influenza Complications Alert Network (FluCAN)

This report summarises the epidemiology of hospitalisations with laboratory-confirmed influenza during the 2018 influenza season