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Research

Programmable DNA endonucleases derived from bacterial genetic defense systems, exemplified by CRISPR-Cas9, have made it significantly easier to perform genomic modifications in living cells. However, unprogrammed, off-target modifications can have serious consequences, as they often disrupt the function or regulation of non-targeted genes and compromise the safety of therapeutic gene editing applications. 

The Kids Research Institute Australia’s Perioperative Medicine team is helping to change global and local practice by finding safer and gentler ways to both undertake surgery, and care for kids and families afterwards.

COMBAT CF is one of two long-standing international trials which have resulted in new early intervention options helping to reduce progressive lung damage in kids living with CF.

A public health campaign to raise awareness about the dangers of chronic wet cough in Aboriginal children is helping to improve detection, diagnosis and management of the condition.

A website providing the latest research and resources on Fetal Alcohol Spectrum Disorder (FASD) is helping parents, educators, health professionals and policy makers navigate the complexities of the neurodevelopmental impairment condition.

Amy Bertinshaw had a choice between ‘wait and see’ or seek help when she noticed her son Stirling was slower to meet developmental milestones at age 12 months.

The WA Kids Cancer Centre has a suite of world-leading research projects to unlock new treatments for childhood cancers.

Healthy skin is a vital factor in the fight against life-threatening conditions like sepsis, heart disease and kidney disease, all of which can be caused by the bacteria Strep A.

Nearly 170 years ago a British doctor applied geospatial mapping to identify the source of a cholera outbreak in central London.

A diet and lifestyle mobile app targeting a critical window in early pregnancy is being introduced to women in the northern suburbs of Perth, hoping to assist with breaking the ‘transmission’ of obesity from one generation to the next.