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Research

Invasive fungal disease (IFD) occurs less frequently during treatment for solid compared to hematological malignancies in children, and risk groups are poorly defined. Retrospective national multicenter cohort data (2004-2013) were analyzed to document prevalence, clinical characteristics, and microbiology of IFD.

News & Events

Have you ever wondered how other parents manage their kids’ device use? As part of a survey for our Cyber Savvy Project, The Kids researchers asked a group of parents for their top tips regarding their child's use of devices.

Brain and behaviour research encompasses a child's learning, development and mental health - and the impact and development of conditions like cerebral palsy, autism and intellectual disability.

News & Events

WA parents and carers can have confidence in sending their children back to school on January 31 with the measures outlined in today’s Safe Return to School Plan.

Research

Medulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine.

Research

To determine the ability to accurately diagnose acute rheumatic fever given the resources available at three levels of the Ugandan healthcare system.

These project websites display extended detailed information about specific research areas.

Research

Elizabeth Graham Smith Hall PhD, MSc, BSc BAppSci PhD CRFS FANZSRS FThorSoc FERS Program Manager Honorary Research Associate 08 6319 1178

The studies this project has conducted

Research

Shakara Yael Bep Liddelow-Hunt Perry Uink BPhil(Hons) BPsych (Hons) MPsych (Clin) PhD BPsych(Hons.), MAppPsy(Clinical), PhD Research Assistant; PhD