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The increase in childhood allergic disease in recent decades has coincided with increased folic acid intakes during pregnancy. Circulating unmetabolized folic acid (UMFA) has been proposed as a biomarker of excessive folic acid intake. We aimed to determine if late-pregnancy serum UMFA and total folate concentrations were associated with allergic disease risk in the offspring at 1 y of age in a population at high risk of allergy.
With well-established evidence that early life conditions have a profound influence on lifespan and health-span, new interventional birth cohorts are examining ways to optimise health potential of individuals and communities. These are aimed at going beyond preventing disease, to the conditions that facilitate flourishing from an early age.
Citation: Ibilola O, Silva D. Environmental (Perinatal) risk factors of ADHD in a sibling control design study. Open Access Journal of Behavioural
This study aimed to identify maternal and family factors that may predict increases or decreases in child eating disorder symptoms over time, accounting for...
The aims of the present study were to (i) examine the relationship between children's degree of adiposity and psychosocial functioning; and (ii) compare patterns of clustering of psychosocial measures between healthy weight and overweight/obese children.
ORIGINS is the largest study of its kind in Australia, following 10,000 children, from their time in the womb, over a decade to improve child and adult health.
ORIGINS is an interventional cohort study, meaning participants receive timely feedback and an action plan to address any potential abnormalities.
Publications, papers and findings coming out of ORIGINS and its sub-projects
An interventional birth cohort researching ways to optimise health and identify conditions that enable every child to flourish from an early age.
A unique national platform delivering faster research at scale to improve the health, wellbeing and equity of children and their parents across Australia