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Showing results for "clinical trials"

About

Learn more about the Wesfarmers Centre of Vaccines and Infectious Diseases

Research

Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life

Appropriate innate immune function is essential to limit pathogenesis and severity of severe lower respiratory infections (sLRI) during infancy, a leading cause of hospitalization and risk factor for subsequent asthma in this age group.

Research

Sexually dimorphic facial features vary according to level of autistic-like traits in the general population

The current data provide support for Bejerot et al.'s androgyny account since males and females with high levels of autistic-like traits generally showed...

Research

Impact of Gastrostomy Placement on Nutritional Status, Physical Health, and Parental Well-Being of Females with Rett Syndrome

Gastrostomy placement was associated with improvement in BMI in females with Rett syndrome, but its long-term impact on individuals and their families is unclear

Research

Effectiveness of clindamycin and intravenous immunoglobulin, and risk of disease in contacts, in invasive group a streptococcal infections

This paper reports on treatment, and preventing infection in close contact, of invasive group A streptococcal (iGAS) using the antibiotic clindamycin and...

Research

Introducing the ORIGINS project: a community-based interventional birth cohort

Non-communicable diseases (NCDs) pose the greatest threat to human health globally. The dramatic rise in early onset NCDs - such as childhood obesity, the allergy epidemic and an increasing burden of mental ill health in children and youth - reflect the profound early impact of modern environments on developing systems.

Research

The impact of monetary incentives on general fertility rates in Western Australia

We examined general fertility rates from 1995 and 2006 by socioeconomic group, maternal age, Aboriginality and location in WA before and after the Baby Bonus.

Research

A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study

Streptococcus pyogenes is a leading cause of infection-related morbidity and mortality. A reinvigorated vaccine development effort calls for new clinically relevant human S pyogenes experimental infection models to support proof of concept evaluation of candidate vaccines. We describe the initial Controlled Human Infection for Vaccination Against S pyogenes (CHIVAS-M75) study, in which we aimed to identify a dose of emm75 S pyogenes that causes acute pharyngitis in at least 60% of volunteers when applied to the pharynx by swab.

Research

Comparing and combining the effects of low dose ultraviolet and physical activity

Shelley Prue Gorman Hart BSc (Hons) PhD BSc (Hons) MSc PhD Honorary Research Associate Honorary Research Fellow shelley.gorman@thekids.org.au

News & Events

Prestigious fellowship for pioneering researcher

Aleksandra Filipovska has been elected a Fellow of the Australian Academy of Health and Medical Sciences.