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Showing results for "Childhood interstitial lung disease "
TNF mRNA expression was higher in leprosy patients compared to endemic controls, but did not differ significantly between clinical subgroups
We hypothesised that the performance of variant prioriisation tools may vary by disease phenotype.
Eight applicants were successful, and were awarded $15,000 each for activities supporting subsequent research grant applications.
Half of the mortality in diabetes is seen in individuals <50 years of age and commonly predicted by the early onset of diabetic kidney disease (DKD). In type 1 diabetes, increased urinary albumin-to-creatinine ratio (uACR) during adolescence defines this risk, but the pathological factors responsible remain unknown.
Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system
Otitis media (OM) is a common childhood disease characterised by middle ear effusion and inflammation.
Advances in gene and molecular technology finally explain why brain tumour cells that look the same, behave and respond differently to treatment.
Accumulating evidence indicates that an early, robust type 1 interferon (IFN) response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an inadequate IFN response associated with disease severity. Our objective was to examine the prophylactic potential of IFN administration to limit viral transmission.
Otitis media (OM) is one of the most common infections in young children, arising from bacterial and/or viral infection of the middle ear. Globally, Streptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi) are the predominant bacterial otopathogens. Importantly, common upper respiratory viruses are increasingly recognized contributors to the polymicrobial pathogenesis of OM.
Seven leading The Kids Research Institute Australia researchers have been awarded Fellowships from the National Health and Medical Research Council (NHMRC).