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Showing results for "Childhood interstitial lung disease "

A phenotype centric benchmark of variant prioritisation tools

We hypothesised that the performance of variant prioriisation tools may vary by disease phenotype.

Interferon β-1a ring prophylaxis to reduce household transmission of SARS-CoV-2: a cluster randomised clinical trial

Accumulating evidence indicates that an early, robust type 1 interferon (IFN) response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an inadequate IFN response associated with disease severity. Our objective was to examine the prophylactic potential of IFN administration to limit viral transmission.

Predominant Bacterial and Viral Otopathogens Identified Within the Respiratory Tract and Middle Ear of Urban Australian Children Experiencing Otitis Media Are Diversely Distributed

Otitis media (OM) is one of the most common infections in young children, arising from bacterial and/or viral infection of the middle ear. Globally, Streptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi) are the predominant bacterial otopathogens. Importantly, common upper respiratory viruses are increasingly recognized contributors to the polymicrobial pathogenesis of OM.

NHMRC Fellowships awarded to support child health research

Seven leading The Kids Research Institute Australia researchers have been awarded Fellowships from the National Health and Medical Research Council (NHMRC).

Could Perth lakes hold the secret to fighting antibiotic-resistant superbugs?

Perth researchers have discovered a predatory virus living in the city’s lakes and rivers that can fight antibiotic-resistant superbugs in children.

Support for kids’ mental health and new cancer therapies boosted by WA Child Research Fund

The Kids Research Institute Australia researchers have been awarded 12 grants in the latest round of funding from the WA Child Health Research Fund (formerly the Telethon-Perth Children’s Hospital Research Fund).

Advances in Vaccines to Prevent Viral Respiratory Illnesses in Children

Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens

Wesfarmers Centre of Vaccines and Infectious Diseases Deborah Lehmann Research Award

The Wesfarmers Centre has established the Deborah Lehmann Research Award to acknowledge the significant contribution that Clinical Associate Professor Deborah Lehmann AO has made to paediatric infectious disease research.

COPD-related modification to the airway epithelium permits intracellular residence of nontypeable haemophilus influenzae

Our findings indicate that COPD, cigarette smoke and macrolide antibiotics potentiate the susceptibility to persistent intracellular NTHi