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Is cellular heterogeneity merely a confounder to be removed from epigenome-wide association studies?DNA methylation is a very sensitive measure of cell fate mix and therefore reveals much about underlying disease etiology including aspects of causation.
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Poverty and child behavioral problems: The mediating role of parenting and parental well-beingThe results show that certain parenting styles, such as psychological control, as well as mothers’ life satisfaction partially mediate the correlation between poverty and child behavioral problems.
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Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan ChildrenIdentified an association between polymorphisms in a long intergenic non-coding RNA (lincRNA) gene (AC011288.2) and pneumococcal bacteremia
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Testing for Response Shift Bias in Evaluations of School Antibullying ProgramsResearchers conducting program evaluations in other contexts are advised to consider testing for this potential source of bias in their studies
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Transcriptome analysis of recurrently deregulated genes across multiple cancers identifies new pan-cancer biomarkersGenomewide expression profiling approach identified a comprehensive set of candidate biomarkers with pan-cancer potential
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Airway epithelial repair in health and disease: Orchestrator or simply a player?This review attempts to highlight migration-specific and cell-extracellular matrix (ECM) aspects of repair used by epithelial cells
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A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiologyDiscover and replicate a locus indexed by rs77728904 at 9p21.3 associated with BCP-ALL susceptibility
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X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genesSystematic sequencing of all X-chromosomal genes in patients with genetic evidence for X-chromosome locus involvement may resolve 58% of Fragile X-negative cases
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Mucin agarose gel electrophoresis: Western blotting for high-molecularweight glycoproteinsConventional methods to separate mucin macromolecules by electrophoresis using an agarose gel and transfer protein into nitrocellulose membrane
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International research utilizing the Early Development Instrument (EDI) as a measure of early child development: Introduction to the Special IssueThis opening paper presents the background to this Special Issue devoted to new international research using Early Development Instrument