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Showing results for "clinical trials"

Immune-modifying properties of topical vitamin D: Focus on dendritic cells and T cells

Topical creams containing the active form of vitamin D (1,25-dihydroxyvitamin D3; 1,25(OH)2D3) or analogues of this compound are currently used with some succes

1,25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responses

The severity of allergic diseases may be modified by vitamin D. However, the immune pathways modulated by the active form of vitamin D, 1,25-dihydroxyvitamin D.

UV inhibits allergic airways disease in mice by reducing effector CD4 T cells

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex

Cytokines of the TGF-β superfamily control essential cell fate decisions via receptor regulated SMAD (R-SMAD) transcription factors. Ligand-induced R-SMAD phosphorylation in the cytosol triggers their activation and nuclear accumulation. We determine how R-SMADs are inactivated by dephosphorylation in the cell nucleus to counteract signaling by TGF-β superfamily ligands. 

Trial determines safest airway device for babies in surgery

A groundbreaking WA trial, published in The Lancet, has determined that a laryngeal mask for babies is preferred over endotracheal tube during minor surgeries

Experts Pledge Global Assault on Kids’ Cancer

A global plan to tackle one of the most aggressive types of childhood brain tumours will be developed as a result of a meeting of international experts in WA.

The research platform - without it, very little happens

At The Kids, every element that enables or facilitates researchers to focus on their important work, is part of the shared 'research platform'. Learn more.

Grants back bold research endeavours

Congratulations to Alec Truswell, Tamara Veselinović, Anastasia Phillips, and Wenna Lee for being awarded Seed Funding through the Wesfarmers Centre of Vaccines & Infectious Diseases, each valued at up to $25,000, and to Sonia McAlister, the recipient of the 2026 Riley Hughes Memorial Award in Pertussis Research.

Diabetes researcher Dr Aveni Haynes awarded prestigious international fellowship

Congratulations to Principal Research Fellow Dr Aveni Haynes from The Kids Research Institute Australia and the University of Western Australia.

Sunlight, nitric oxide and cardiometabolic dysfunction: exploring beneficial mechanisms

Prue Shelley Hart Gorman BSc (Hons) MSc PhD BSc (Hons) PhD Honorary Research Fellow Honorary Research Associate prue.hart@thekids.org.au