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Achieving lasting change in the Kimberley

Many people would be daunted when tasked with coordinating, from scratch, a new The Kids Research Institute Australia satellite site to service WA’s north. But not John Jacky

Wal-yan researchers welcomed at scientific meeting in New Zealand

More than 14 researchers from the Wal-yan Respiratory Research Centre will be welcomed as presenters and facilitators at The Thoracic Society of Australia and New Zealand and The Australia and New Zealand Society of Respiratory Science (TSANZSRS) Annual Scientific Meeting (ASM) this weekend.

Cerebral Palsy Respiratory Health

We know from research that the risk of death from respiratory disease is 14 times higher for adults with cerebral palsy than for other adults. Respiratory disease is the most common cause of premature death in children and young people with cerebral palsy and one of the main causes of hospitalisation.

Nasal Delivery of Haemophilus haemolyticus Is Safe, Reduces Influenza Severity, and Prevents Development of Otitis Media in Mice

Despite vaccination, influenza and otitis media (OM) remain leading causes of illness. We previously found that the human respiratory commensal Haemophilus haemolyticus prevents bacterial infection in vitro and that the related murine commensal Muribacter muris delays OM development in mice. The observation that M muris pretreatment reduced lung influenza titer and inflammation suggests that these bacteria could be exploited for protection against influenza/OM.

Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy

Time-critical transcriptional events in the immune microenvironment are important for response to immune checkpoint blockade (ICB), yet these events are difficult to characterise and remain incompletely understood. Here, we present whole tumor RNA sequencing data in the context of treatment with ICB in murine models of AB1 mesothelioma and Renca renal cell cancer. 

Defining Group A Streptococcus interaction with the tonsil epithelium to inform vaccine development

A vaccine that prevents the initial attachment of Strep A to the tonsils would reduce the incidence of Strep throat and severe diseases that result.

Evaluation of a bacterial therapy for prevention of respiratory infection including influenza and otitis media

Deborah Lea-Ann Peter Ruth Strickland Kirkham Richmond Thornton PhD PhD MBBS MRCP(UK) FRACP PhD Head, Pregnancy and Early Life Immunology Co-Head,

Improved diagnosis, treatment and prevention of recurrent tonsillitis

Strep A causes over 775 million infections each year world-wide, including over 615 million cases of tonsil infection (Strep throat).

Study of an oral medication for infants hospitalized with Respiratory Syncytial Virus (RSV) infection

Christopher Jennifer Peter Blyth Kent Richmond MBBS (Hons) DCH FRACP FRCPA PhD RN MBBS MRCP(UK) FRACP Centre Head, Wesfarmers Centre of Vaccines and

PneumoWA: A case-control study of the role of viral and bacterial pathogens in causing pneumonia among Western Australian children

Christopher Elke Jennifer Peter Tom Blyth Seppanen Kent Richmond Snelling MBBS (Hons) DCH FRACP FRCPA PhD BSc PhD RN MBBS MRCP(UK) FRACP BMBS DTMH