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Immune-modifying properties of topical vitamin D: Focus on dendritic cells and T cells

Topical creams containing the active form of vitamin D (1,25-dihydroxyvitamin D3; 1,25(OH)2D3) or analogues of this compound are currently used with some succes

UV inhibits allergic airways disease in mice by reducing effector CD4 T cells

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

Sunlight, nitric oxide and cardiometabolic dysfunction: exploring beneficial mechanisms

Prue Shelley Hart Gorman BSc (Hons) MSc PhD BSc (Hons) PhD Honorary Research Fellow Honorary Research Associate prue.hart@thekids.org.au

The Sun Safe app: a new online tool to promote safe sun behaviours by teenagers

Gail Prue Shelley Alvares Hart Gorman PhD BSc (Hons) MSc PhD BSc (Hons) PhD Principal Research Fellow Honorary Research Fellow Honorary Research

Altered immunity and dendritic cell activity in the periphery of mice after long-term engraftment with bone marrow from ultraviolet-irradiated mice

To investigate the immune capabilities of peripheral tissue DCs generated in vivo from the BM of UV-irradiated mice, chimeric mice were established.

Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow

Injection of BM-differentiated DCs from nonchimeric mice restored the reduced immune responses of PGE2-chimeric mice.

Acute Erythemal Ultraviolet Radiation Causes Systemic Immunosuppression in the Absence

Vitamin D is synthesised by ultraviolet (UV) irradiation of skin and is hypothesized to be a direct mediator.

Toward homeostasis: Regulatory dendritic cells from the bone marrow of mice with inflammation

Inflammatory mediators from peripheral tissues may control dendritic cell (DC) development in the bone marrow.

Modulation of the immune system by UV radiation: More than just the effects of vitamin D?

Humans obtain most of their vitamin D through the exposure of skin to sunlight

Vitamin D deficiency causes deficits in lung function and alters lung structure

The prevalence of vitamin D deficiency is increasing and has been linked to obstructive lung diseases including asthma and chronic obstructive pulmonary disease