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Data indicate a role for Interferonβ in linking viral infection and allergy
We investigated the ability of topical 1,25(OH)2D to suppress contact dermatitis through an IL9 dependent process, examining mast cells and IL9 secreting cells.
Prue Shelley Hart Gorman BSc (Hons) MSc PhD BSc (Hons) PhD Honorary Research Fellow Honorary Research Associate prue.hart@thekids.org.au
Gail Prue Shelley Alvares Hart Gorman PhD BSc (Hons) MSc PhD BSc (Hons) PhD Principal Research Fellow Honorary Research Fellow Honorary Research
Shelley Prue Gorman Hart BSc (Hons) PhD BSc (Hons) MSc PhD Honorary Research Associate Honorary Research Fellow shelley.gorman@thekids.org.au
We tested whether there is a causal association between vitamin D deficiency, airway smooth muscle (ASM) mass, and the development of airway hyperresponsiveness
In summary, UV-BMDCs do not express the classical phenotypic or gene expression properties of DCs reported by others as 'regulatory' or 'tolerogenic'.
To investigate the immune capabilities of peripheral tissue DCs generated in vivo from the BM of UV-irradiated mice, chimeric mice were established.
Injection of BM-differentiated DCs from nonchimeric mice restored the reduced immune responses of PGE2-chimeric mice.
Vitamin D is synthesised by ultraviolet (UV) irradiation of skin and is hypothesized to be a direct mediator.