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Researchers from the Children’s Diabetes Centre have had a lead role in a global adolescent Type 1 Diabetes study.
Enteroviruses (EVs) have long been implicated in the development of islet autoimmunity (IA) and type 1 diabetes. However, given the ubiquity of EV infections in children, disease susceptibility is likely driven by host-specific immune responses rather than viral exposure alone.
Islet autoantibodies herald early type 1 diabetes. However, less is known of the evolution of autoantibodies to the islet autoantigen ZnT8. Our primary aim was to characterise the development of islet autoantibodies in a pregnancy-birth at-risk cohort and to provide new knowledge about ZnT8A.
This study evaluated the relationship between cat allergen–specific biomarkers in adults with cat allergy with and without cat ownership.
We have been working with young people with T1D, other researchers and app developers to create a new smartphone exercise app called acT1ve.
It’s hard to believe that 20 years has passed since April Welsh, 5, was pictured with Professor Tim Jones in a story about type 1 diabetes research. Plenty has changed but one constant remains — Professor Jones still works for WA’s only paediatric diabetes service which celebrates its 50th year.
Iatrogenic hypoglycaemia is one of the main limiting factors in the glycaemic management of diabetes. It causes negative biological, psychological, and social consequences in most people with type 1 diabetes and in many with advanced type 2 diabetes. This chapter explores physiological homeostatic mechanisms that prevent hypoglycaemia through glucose counter-regulation, before discussing specific acquired defects of glucose counter-regulation in diabetes, which provides an insight into risk factors for hypoglycaemia.
The presence of pleural plaques on radiologic imaging does not confer additional increase in the risk of lung cancer
The aim of this study was to examine the gene response of white blood cells in severe allergic reactions to identify genes that could be targets to new drugs...
Principal Research Fellow