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Hypoglycaemia in Diabetes

Iatrogenic hypoglycaemia is one of the main limiting factors in the glycaemic management of diabetes. It causes negative biological, psychological, and social consequences in most people with type 1 diabetes and in many with advanced type 2 diabetes. This chapter explores physiological homeostatic mechanisms that prevent hypoglycaemia through glucose counter-regulation, before discussing specific acquired defects of glucose counter-regulation in diabetes, which provides an insight into risk factors for hypoglycaemia.

Genomic responses during acute human anaphylaxis are characterized by upregulation of innate inflammatory gene networks

The aim of this study was to examine the gene response of white blood cells in severe allergic reactions to identify genes that could be targets to new drugs...

T-Cell Expression and Release of Kidney Injury Molecule-1 in Response to Glucose Variations Initiates Kidney Injury in Early Diabetes

Half of the mortality in diabetes is seen in individuals <50 years of age and commonly predicted by the early onset of diabetic kidney disease (DKD). In type 1 diabetes, increased urinary albumin-to-creatinine ratio (uACR) during adolescence defines this risk, but the pathological factors responsible remain unknown.

School experience studies

Besides the challenges associated with their teenage years, adolescents with Type 1 Diabetes (T1D) encounter additional challenges of having a chronic condition.

Congratulations Centre Researchers

Centre researchers awarded external travel grants to attend international conferences

Dr Shaun Teo and Dr Paul Fournier awarded Diabetes Australia grants

A big congratulations to our The Kids and UWA researchers Dr Shaun Teo and Dr Paul Fournier who have both been awarded $70,000 grants for their diabetes research projects, under the 2023 Diabetes Australia Research Program (DARP).

Combating glucose rises after meals - new study

Participants are needed for a new Children's Diabates Centre study looking at the patterns in glucose rise after meals.

Exercise summit wrap up

The Children’s Diabetes Centre recently held summits for young people with Type 1 Diabetes to get their input into the development of new exercise guidelines.

Family’s fundraising efforts a hole-in-one

When Meghan Bunter’s daughter was first diagnosed with diabetes, she felt overwhelmed not only with Ella’s diagnosis but also the flood of donation requests.