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Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary diseaseChronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function
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Relationship between out-of-home care placement history characteristics and educational achievement: A population level linked data study.This study examined the influence of placement stability, reunification, type of care, time in care and age at entry to care on children's educational outcomes.
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New Opportunities for Evidence in Fetal Alcohol Spectrum DisorderRecent research, using objective 3-dimensional facial imaging, has found differences between the facial shape of individuals with FAS and the facial shape of individuals without FAS or with partial FAS
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Vaccine hesitancy, refusal and access barriers: The need for clarity in terminologyWe propose more precision in the term 'vaccine hesitancy' is needed particularly since much under-vaccination arises from factors related to access
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Content validation of the Quality of Life Inventory—DisabilitySatisfactory content validity is reported, where ongoing consumer feedback shaped the dataset from which the final items were selected
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Requirements for improving health and well-being of children with Prader-Willi syndrome and their familiesPrader-Willi syndrome (PWS) is a rare genetic condition with multi-system involvement
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Panel 8: Vaccines and immunologyReview and highlight of the significant advances made towards vaccine development and understanding of the immunology of otitis media
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Improvement in Psychosocial Outcomes in Children with Type 1 Diabetes and Their Parents Following Subsidy for Continuous Glucose MonitoringIntroduction of subsidized CGM showed early improvement in psychosocial and glycemic outcomes in patients and their families in Western Australia
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Choosing primary endpoints for clinical trials of health care interventionsThis narrative review describes the evolution, range and relative strengths and weaknesses of endpoints used in late phase trials
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Genetic determinants of paediatric food allergy: A systematic reviewWe systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation