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Showing results for "clinical trials"

Lung function following very preterm birth in the era of 'new' bronchopulmonary dysplasia

The pathophysiology of BPD has changed in recent years as advances in neonatal care have led to increased survival of smaller, more preterm, infants who...

Prevalence, repairs and complications of hypospadias: An Australian population-based study

To investigate hypospadias' prevalence and trends, rate of surgical repairs and post-repair complications in an Australian population.

Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia.

This study describes the development and molecular characterization of a panel of patient-derived infant leukemia oncogene xenografts and their sensitivity...

CAGE-defined promoter regions of the genes implicated in Rett Syndrome

A comprehensive picture of the regulatory regions of the three genes involved in Rett Syndrome

Reliability and Validity of a Short Version of the General Functioning Subscale of the McMaster Family Assessment Device

The findings of this study support the use of a GF6+ subscale from the FAD, as a quick and effective tool to assess the overall functioning of families

Hospital costs of multiple-birth and singleton-birth children during the first 5 years of life and the role of assisted reproductive technology

The objective was to conduct a comprehensive economic and health services assessment of the frequency, duration, and cost of hospital admissions during the...

Respiratory Syncytial Virus Transmission in Closed Community Settings That Include Children: A Systematic Review and Meta-Analysis

Respiratory syncytial virus (RSV) is a leading cause of severe respiratory infections in children and is predominantly acquired and spread in community settings such as households and early childhood education centres. This review aims to synthesise the available evidence on RSV transmission in closed community settings that include children, with a focus on secondary attack rates.

Longitudinal Study of Language of Twins at Ages 9 and 14 Years: Twinning, Zygosity, and Heritability

This unprecedented longitudinal twin study focused on the arc of language acquisition from first words to adolescence, with data collection at 2, 4, and 6 years of age, reported in four previous studies and now new data at ages 9 and 14 years.

Australia’s top 10 rare disease research priorities: a priority setting partnership

The aim of this study was to identify and prioritise the ten most important unanswered themes in rare disease research in Australia by integrating perspectives of key stakeholders, including people living with rare disease, parents/carers, health professionals, and rare disease community advocates.

Reduced Type-I Interferon by Plasmacytoid Dendritic Cells and Asthma in School-Aged Children

Allergic sensitization and reduced ability to respond to viral infections may contribute to virus-induced wheeze and asthma development in young children. Plasmacytoid dendritic cells (pDC) are rare immune cells that produce type I interferons (IFN-I) and play a key role in orchestrating immune responses against viruses.