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Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrity

In disease settings, vitamin D may be important for maintaining optimal lung epithelial integrity and suppressing inflammation, but less is known of its effects prior to disease onset.

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries

These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development.

Repeated stress in pregnancy linked to children's behaviour

Research has found a link between the number of stressful events experienced during pregnancy and increased risk of behavioural problems in children.

Available Data & Biological Samples

ORIGINS is collecting data from multiple sources from the mother, infant and partner at multiple timepoints from gestation through to five years of age.

Publications

Browse the published work of the Centre's researchers

Spotting sporotrichosis skin infection: The first Australian paediatric case series

These data highlight the importance of recognising Sporotrichosis in children outside an outbreak setting

Current research

Phage WA have a number of projects underway and these cover a broad range of phage research areas.

Clinical Management of Staphylococcus aureus Bacteremia in Neonates, Children, and Adolescents

Staphylococcus aureus is a common cause of community and health care-associated bacteremia, with authors of recent studies estimating the incidence of S aureus bacteremia (SAB) in high-income countries between 8 and 26 per 100 000 children per year. Despite this, <300 children worldwide have ever been randomly assigned into clinical trials to assess the efficacy of treatment of SAB.

Global Disease Modelling

We help shape how the world responds to infectious diseases: guiding vaccine and treatment development, and advising on public health measures to control and eliminate disease. Our mathematical models capture how diseases spread, how severe infections are, and how childhood exposure shapes health across a lifetime.