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News & Events
Bill & Melinda Gates Foundation Grant aims to prevent deadly infections in early lifeNewborn babies and their fragile immune systems struggle to fight off nasty infections such as septicaemia, pneumonia and gastroenteritis.
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The Kids Research Institute Australia researcher recognised for saving children in PNGClinical Associate Professor Deborah Lehmann has been recognised for her dedication to reducing the burden of infectious diseases in Papua New Guinea (PNG) with an award supporting research in the Western Pacific named in her honour.
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Prestigious invite for WA infectious disease expertsTwo Perth clinician-scientists have been recognised as national leaders in infectious disease research after being elected as Fellows of the esteemed Australian Academy of Health and Medical Sciences.
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Major funding announced to kickstart key WCVID projectsThe Wesfarmers Centre of Vaccines and Infectious Diseases (WCVID) awarded three successful recipients with Catalyst research grants, with each researcher receiving $80,000 towards their chosen project.
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Australia on the cusp of one-shot meningococcal protectionA life-saving meningococcal vaccine covering all five common strains of the deadly disease could soon be available thanks to vital research demonstrating the safety and effectiveness of a combination Men ABCWY vaccine.
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Kids researchers using real tonsils in quest to develop new Strep A vaccineA new study underway at the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, is deliberately infecting tonsils with Strep A in the laboratory to test a range of potential vaccine candidates.
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COVID-19 risks explained for babies, children and pregnant womenMany parents may be feeling anxious and confused about what COVID-19 means for pregnant women, babies and children.
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Multi-million-dollar investment in child health to support vital researchFour The Kids Research Institute Australia researchers have received prestigious fellowships and four significant cohort studies led or co-led by The Kids have received key grants under two new funding programs supported by the State Government’s Future Health Research and Innovation (FHRI) Fund.
Research
Cardiac monitoring safety assessment framework for early phase group a streptococcal vaccine trialsThis paper presents a comprehensive cardiac safety framework for early clinical development of Streptococcus pyogenes (Group A Streptococcus) vaccines, endorsed by the Strep A Vaccine Global Consortium and the Australian Strep A Vaccine Initiative. Given historical concerns about vaccine-associated acute rheumatic fever, we have established standardized echocardiography protocols integrated with clinical assessment for monitoring cardiac safety in early-phase vaccine trials.
Research
Respiratory Syncytial Virus Strain Evolution and Mutations in Western Australia in the Context of Nirsevimab ProphylaxisNirsevimab is a long-acting monoclonal antibody used to prevent respiratory syncytial virus (RSV) infection in infants and high-risk children. During the 2024 RSV season in Western Australia, 21 922 doses were administered to infants entering their first season and 1221 doses to at-risk children. In this context, the selection and spread of escape variants are a potential concern. This study aimed to investigate nirsevimab binding site mutations using clinical and wastewater data.