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Research

A phenotype centric benchmark of variant prioritisation tools

We hypothesised that the performance of variant prioriisation tools may vary by disease phenotype.

Research

Early autism symptoms in infants with tuberous sclerosis complex

We examined early signs of ASD in infants wit tuberous sclerosis complex, approximately 50% of whom will meet criteria for ASD by age 3.

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Investigating the long-term impact of a childhood sun-exposure intervention, with a focus on eye health: protocol for the Kidskin-Young Adult Myopia Study

A follow-up of Kidskin Study participants provides an opportunity to investigate the associations between a childhood sun-exposure intervention and potentially related conditions in adulthood

Research

Cyber-Friendly Schools

This chapter describes a whole-school cyberbullying intervention developed and evaluated in Western Australia with secondary school students aged 13–18 years old

Research

Cerebral palsy and genomics: an international consortium

Accumulating evidence of the role of genetic variation in CP aetiology suggests that individuals with CP should undergo genomic testing as part of their diagnostic workup

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Rheumatic Heart Disease Worldwide: JACC Scientific Expert Panel

The authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care

Research

Worldwide variation in human milk metabolome: Indicators of breast physiology and maternal lifestyle?

This study investigates the variation of human milk metabolites in human milk between five different countries

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The Canmore Declaration: Statement of Principles for Planetary Health

We provide the Canmore Declaration, a Statement of Principles for Planetary Health

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Vagus nerve stimulation for the treatment of refractory epilepsy in the CDKL5 Deficiency Disorder

Our study suggests that vagus nerve stimulation is a generally safe and effective adjunct treatment for CDKL5-associated epilepsy

Research

Epigenetic dysregulation of host gene expression in Toxoplasma infection with specific reference to dopamine and amyloid pathways

Our results provide a possible functional link between Toxoplasma gondii infection and congenital/early life and adult neurological clinical signs