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Poly-arginine and arginine-rich peptides are neuroprotective in stroke modelsUsing cortical neuronal cultures and glutamic acid excitotoxicity and oxygen-glucose deprivation (OGD) stroke models, we demonstrated that poly-arginine and...
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New genetic loci link adipose and insulin biology to body fat distributionPathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing...
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Early pulmonary inflammation and lung damage in children with cystic fibrosisAirway inflammation and infection are present from early in life, often before children are symptomatic.
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The microbiology of impetigo in Indigenous childrenPrevalence and antimicrobial resistance of impetigo pathogens in a randomised, controlled trial of impetigo treatment conducted in remote Indigenous communities
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Acute rheumatic fever and rheumatic heart disease: Incidence and progression in the Northern Territory of Australia 1997 -2010The reduction in ARF recurrence indicates that the RHD control program has improved secondary prophylaxis; a decline in RHD incidence is expected to follow.
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Size-Dependent Uptake of Particles by Pulmonary Antigen-Presenting Cell PopulationsThe respiratory tract is an attractive target organ for novel diagnostic and therapeutic applications with nano-sized carriers, but their immune effects and...
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Evidence for Distinct Cognitive Profiles in Autism Spectrum Disorders and Specific Language ImpairmentThis finding supports distinct cognitive profiles in ASD and SLI and may provide further evidence for distinct aetiological mechanisms in the two conditions.
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The western dietary pattern is prospectively associated with nonalcoholic fatty liver disease in adolescenceIn centrally obese adolescents with NAFLD, a healthy dietary pattern may be protective, whereas a Western dietary pattern may increase the risk.
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Exploring the potential to use data linkage for investigating the relationship between birth defects and prenatal alcohol exposureThere was a significant association between maternal alcohol-related diagnoses recorded during pregnancy and ARBD, with an attributable fraction of 0.57%.
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Recombinant house dust mite allergensHouse dust mites (HDM) are a globally important source of allergen responsible for the sensitization of more than 50% of allergic patients.