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Burkholderia pseudomallei is a facultative intracellular pathogen and the causative agent of melioidosis. Treatment of this deadly infection is both protracted and limited to only a select number of antibiotics. Not only can patients suffer adverse reactions to prolonged therapy, but resistance has also been reported in several clinical isolates.
Around the world, adolescents are more digitally connected than ever, and access to digital devices has become a lightning rod of conflict in many homes. To date, research on best practices in digital parenting has been hampered by the absence of a well validated measure that reflects the mutli-faceted realities of parenting in the contemporary digital age.
Two RSV immunisations products: a maternal vaccine, Abrysvo, and a long-acting monoclonal antibody, nirsevimab, both designed to prevent RSV illness in infants, have recently become available. Modelling evidence is required to inform how to optimally use these products in immunisation programs to reduce the burden of RSV in young children.
Sibling profiles, including sibling status (only-child or sibling) and sibling characteristics (sibling size, birth order, and sex), can impact on lived experiences and social interactions, and operate as protective or risk factors for a wide range of health and well-being indicators and outcomes. Using population-based data linkage to disability-specific databases, sibling profiles were compared between families of children with and without neurodevelopmental conditions.
Cognitive theories contend that attentional bias to negative information contributes to elevated trait anxiety. However, research in this area has been hindered by the lack of a standardized assessment task that demonstrates the required qualities, including strong internal consistency and ecological validity. The present study aimed to develop and validate the Talking Heads Attentional Bias Assessment Task, an easy-to-implement measure that overcomes the limitations of previous attentional bias assessment tasks.
Rheumatic heart disease remains a major public health challenge in Ethiopia, particularly among children. Monthly intramuscular benzathine penicillin G is the cornerstone of secondary prophylaxis, yet adherence and delivery are suboptimal. This study explores the lived experiences of children and adolescents with RHD, capturing their direct voices and those of their caregivers to understand determinants of secondary prophylaxis uptake.
Rheumatic heart disease (RHD) is the acquired autoimmune heart valve damage resulting from untreated infection with the Streptococcus pyogenes bacterium, which affects people experiencing socioeconomic disadvantage globally. This study measured RHD-associated major adverse cardiovascular events (MACE) and the increased risk associated with pregnancy among women diagnosed with RHD.
Human milk is characterised by its complex composition, consisting of nutrient and bioactive components that play a crucial role in infant health. Although the infant oral cavity is directly exposed to these components during breastfeeding, their effects on the developing oral microbiome remains underexplored.
Individuals living with type 1 diabetes (T1D) are at an increased risk of experiencing psychological distress; however, there remains a scarcity of scalable and widely accessible support services, particularly for adolescents and young adults. To address this gap, digital mental health interventions are becoming an increasingly important area of innovation in diabetes care.
The proliferation of fast-food outlets in residential areas has raised growing concerns about their impact on community health, safety, and wellbeing. This qualitative study examined both pre-development community consultation submissions and post-development resident experiences surrounding the development of a McDonald's outlet in a newly established suburb on the urban fringe of Perth, Western Australia.