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Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapyTopical application of tumors with the TLR7 agonist imiquimod is an effective adjunct treatment for a range of primary dermatological cancers.
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Rio Tinto Child Health Partnership Final ReportIn 2002, the Founding Director of The Kids for Child Health Research, Professor Fiona Stanley, approached Rio Tinto Ltd about the possibility...
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Unpacking the complex nature of the autism epidemicThis paper discusses changes in diagnostic criteria, decreasing age at diagnosis, improved case ascertainment, diagnostic substitution, and social influences.
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Monitoring child abuse and neglect at a population level: patterns of hospital admissions for maltreatment and assaultTo investigate the prevalence, trends, and characteristics of maltreatment and assault related hospital admissions and deaths among children;
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Low-moderate prenatal alcohol exposure and risk to child behavioural development: a prospective cohort studyTo examine the association of fetal alcohol exposure during pregnancy with child and adolescent behavioural development.
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Early immunological influences on asthma development: opportunities for early interventionEarly immunological influences on asthma development: opportunities for early intervention
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Increased longevity and the comorbidities associated with intellectual and developmental disabilityThe contributors, all world experts in their fields, also discuss what we can learn from the presence of co-morbidities.
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Hypoglycemia alarm enhancement using data fusionThe acceptance of closed-loop blood glucose (BG) control using continuous glucose monitoring systems (CGMS) is likely to improve.
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Airway narrowing assessed by anatomical optical coherence tomography in vitro: dynamic airway wall morphology and functionPrevious histological and imaging studies have shown the presence of variability in the degree of bronchoconstriction of airways sampled at different locations.
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Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cellsTumor cell death potentially engages with the immune system. However, the efficacy of anti-tumor chemotherapy may be limited by tumor-driven...