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Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function from childhood into adulthood

Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may increase risk for asthma and allergies. However, little is known about the long-term effects of early life exposure to these compounds.

Using lung function measurements to greater advantage in patients with lung disease: Which test and when?

This paper is an introduction to a series of articles about improved measurement of lung function in patients with chronic lung disease.

Lung Clearance Index and Structural Lung Disease on Computed Tomography in Early Cystic Fibrosis

Lung Clearance Index and Structural Lung Disease on Computed Tomography in Early Cystic Fibrosis Abstract Rationale: The lung clearance index is a

Kawasaki disease, childhood allergy and the hygiene hypothesis

Kawasaki disease is characterized by increased inflammation

Epidemiology of T2DM in childhood and associated disease complications

Investigating the incidence of childhood Type 2 Diabetes in the Western Australian community

Small macrophages are present in early childhood respiratory disease

Recently, an established "small macrophage" phenotype has been observed in the sputum of patients with CF and COPD. However, little is known about the...

Research priority setting in childhood chronic disease: a systematic review

Research priority setting activities in paediatric chronic disease cover many discipline areas and have elicited a broad range of topics

New study to better understand how bronchiectasis develops during childhood

A new research project – the WA Paediatric Bronchiectasis Cohort Study – officially commenced this month with the aim of looking at children with bronchiectasis in Western Australia, like nine-year-old Holly (pictured), to better understand how this disease develops during childhood.

Infection and the development of allergic disease

An improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in protein...

Bronchiectasis Research for Improving Lung Health outcomes and Treatment (BRIGHT)

This prospective, longitudinal cohort study will examine airway sputum, lung function, and clinical surveillance data of children with bronchiectasis attending Perth Children’s Hospital.