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Research

Using a large international sample to investigate epilepsy in Rett syndrome

The aim of this study was to identify characteristics of epilepsy in Rett syndrome (RTT), and relationships between epilepsy and genotype.

Research

Maternal vitamin D levels during pregnancy and offspring eating disorder risk in adolescence

This is the first study to link low gestational vitamin D to increased eating disorder risk in female offspring of Caucasian mothers.

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Altered immunity and dendritic cell activity in the periphery of mice after long-term engraftment with bone marrow from ultraviolet-irradiated mice

To investigate the immune capabilities of peripheral tissue DCs generated in vivo from the BM of UV-irradiated mice, chimeric mice were established.

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The effect of midday moderate-intensity exercise on postexercise hypoglycemia risk in individuals with type 1 diabetes

Recently we reported a biphasic increase in glucose requirements to maintain euglycemia after late-afternoon exercise, suggesting a unique pattern of delayed...

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A population-based study of risk factors for severe hypoglycaemia in a contemporary cohort of childhood-onset type 1 diabetes

The aim of this study was to examine the incidence rates and risk factors associated with severe hypoglycaemia in a contemporary cohort of children and...

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Familial aggregation of childhood and adult cancer in the Utah genealogy

We explored familial aggregation of cancer in a population-based case-control study using genealogical record linkage and designed to overcome limitations of...

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Assessment and management of nutrition and growth in rett syndrome

We developed recommendations for the clinical management of poor growth and weight gain in Rett syndrome through evidence review and the consensus of an...

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The case for global investment in rheumatic heart-disease control

The review built a case for extending simple and cost–effective measures to all countries. Had these recommendations been put into action, significant...

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Epigenetics in infectious diseases

Viruses, bacteria, and parasites have developed strategies to invade and establish long-term infections in their hosts.

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A three generation study of the mental health relationships between grandparents, parents and children

It is well known that children of parents with mental illness are at greater risk of mental illness themselves.