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Anoctamins and Calcium Signalling: An Obstacle to EGFR Targeted Therapy in Glioblastoma?

Glioblastoma is the most common form of high-grade glioma in adults and has a poor survival rate with very limited treatment options. There have been…

Cancer therapies inducing DNA damage

The induction of DNA damage has been employed as an anticancer strategy for more than 100years, first starting with the use of radiation to treat sto…

Type I interferon subtypes differentially activate the anti-leukaemic function of natural killer cells

Natural killer (NK) cells have an intrinsic ability to detect and eliminate leukaemic cells. Cellular therapies using cytokine-activated NK cells hav…

Innovative Playful Learning Approaches to Improve Children’s Readiness for Primary Education in Uzbekistan

The Government of Uzbekistan has committed to reforming preschool education, prioritising upskilling teachers to use international best practice.

Review of trends in disabilities, mental health disorders and complex needs among children and adolescents

The aim of the project was to provide the South Australian Department for Education with a synthesis of high-quality evidence on the population preva…

Learning Together and Learning Together at Home: Program Model Review

Learning Together, developed by the South Australian Department for Education, aims to create enriched learning environments that can be transferred…

Early literacy skills: review of evidence for pedagogical approaches that best support children’s early literacy skills

Recent evidence indicates that a child’s home learning environment is the strongest predictor of success in later reading abilities and that for chil…

School staff responses to student reports of bullying: A scoping review

Bullying in schools has been associated with poor academic and mental health outcomes in students. While students are often encouraged to report bull…

Epstein–Barr virus infection, B-cell dysfunction and other risk factors converge in gut-associated lymphoid tissue to drive the immunopathogenesis of multiple sclerosis: a hypothesis

Multiple sclerosis is associated with Epstein–Barr virus (EBV) infection, B-cell dysfunction, gut dysbiosis, and environmental and genetic risk facto…

Tissue-resident memory T cells in the era of (Neo) adjuvant melanoma management

Tissue-resident memory T (TRM) cells have emerged as key players in the immune control of melanoma. These specialized cells are identified by express…