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Effects of simulated tidal and deep breathing on immature airway contraction to acetylcholine and nerve stimulationIn adults, respiratory movements, such as tidal and deep breaths, reduce airway smooth muscle force and cause bronchodilation.
Research
Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cellsTumor cell death potentially engages with the immune system. However, the efficacy of anti-tumor chemotherapy may be limited by tumor-driven...
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Hemispheric division of function is the result of independent probabilistic biasesCausal theories propose that functional asymmetry is an obligatory pattern of organisation, while statistical theories maintain this is a reflection...
Research
Adult psychosocial outcomes of children with specific language impairment, pragmatic language impairment and autismEvidence that some children also develop autistic symptomatology over time has raised suggestions that developmental language disorder...
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The common BDNF polymorphism may be a modifier of disease severity in Rett syndromeRett syndrome (RTT) is caused by mutations in the transcriptional repressor methyl CpG-binding protein 2 (MECP2).
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Impact of scoliosis surgery on activities of daily living in females with Rett syndromeScoliosis is a common orthopaedic complication of Rett syndrome, and surgery is commonly used to reduce asymmetry in cases with severe scoliosis.
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Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolismWe examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection.
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Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapyTopical application of tumors with the TLR7 agonist imiquimod is an effective adjunct treatment for a range of primary dermatological cancers.
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Potent bronchodilation and reduced stiffness by relaxant stimuli under dynamic conditionsAirway relaxation in response to isoprenaline, sodium nitroprusside (SNP) and electrical field stimulation (EFS) was compared under static and dynamic...
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Investigations into the role of ST2 in acute asthma in childrenThis study investigated the potential role of ST2 in children with acute asthma.