RISE has a clear vision: to reduce the health and economic burden of RSV through effective and equitable immunisation.
Infection Triggered Encephalopathy Syndrome (ITES) is a rare but potentially severe complication of infections in children. ITES is a syndrome of acute encephalopathy that occurs in the context of a febrile illness and hypothesised to result from a…
Parkinson’s disease (PD) is a progressive neurodegenerative disorder in which mechanisms linking metabolic dysregulation to neuronal vulnerability remain incompletely understood. Increasing evidence suggests that dysregulation of lipid metabolism pl…
Mucus plugs have been previously recognized as an important pathological feature in asthma and chronic obstructive pulmonary disease (COPD), but their clinical role in these diseases has not been explored in depth until recently. Mucus plug formatio…
Cystic fibrosis (CF) is a genetic condition caused by mutation of the cystic fibrosis transmembrane regulator (CFTR) gene. Recently licensed modulator therapies target the defective CFTR protein and have transformed the formerly life-limiting trajec…
Rates of anaphylaxis in early childhood are rising, yet there remains a paucity of data on age-specific presentations and outcomes. While prompt treatment is essential, symptoms can differ from older children. Observation after stabilization is rout…
Real-time analysis of epidemic trends and forecasts can help support public health planning and the response to seasonal respiratory disease. Here, we present two models that were used in a 2025 New Zealand winter situational assessment programme fo…
Intranasal vaccines offer a needle-free strategy to enhance immunity to respiratory infections. We investigated the mechanism of action of a novel intranasal vaccine using the human respiratory commensal Haemophilus haemolyticus, previously shown to…
This study describes the carer- and self-reported mealtime challenges for children and young people with cerebral palsy. These data are novel and incorporate the consumer's perspective to inform service delivery.