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Lung transcriptomics studies in asthma have provided valuable information in the whole lung context, however, deciphering the individual contributions of the airway and parenchyma in disease pathogenesis may expedite the development of novel targeted treatment strategies. In this study, we performed transcriptomics on the airway and parenchyma using a house dust mite (HDM)-induced model of experimental asthma that replicates key features of the human disease.
Research question: Are asthma and allergies more common in adolescents conceived with assisted reproductive technologies (ART) compared with adolescents conceived without?
Two outstanding researchers from the Wal-yan Respiratory Research Centre have been awarded a 2022 Innovation Fellowship supported by the WA Government's Future Health Research and Innovation (FHRI) Fund.
Flare-ups of asthma are usually brought on by respiratory infections, such as the common cold, and are one of the most common reasons for a child to miss school or require emergency care.
A new study has found a common asthma drug is effective for some very premature babies who go on to suffer from lung complications.
A study led by The Kids Research Institute Australia has suggested vitamin D supplementation in babies is no match for sunlight when it comes to preventing eczema.
Wheezing and asthma exacerbations are leading causes of pediatric hospital admissions. Predicting which children will experience persistent exacerbations remains challenging. Prior research has identified immune endotypes in the nasal epithelium of children with acute asthma and wheezing, characterized by varying balances of interferons and inflammatory markers. Notably, children exhibiting low interferon responses coupled with high inflammation are at an increased risk for recurrent respiratory exacerbations.
Telethon Institute for Child Health Research scientist Dr Anthony Bosco has been recognised for his cutting edge research investigating asthma attacks
Deborah Pat Strickland Holt PhD PhD, DSc, FRCPath, FRCPI, FAA Head, Pregnancy and Early Life Immunology Emeritus Honorary Researcher Deb.Strickland@
The Metabolomics to Predict Asthma (MAP) study has reached an important turning point. After examining the ‘chemical fingerprints’ of more than 300 children, the team is now taking a new approach, turning to proteins to better understand which young children with recurrent wheeze go on to develop asthma.