The BCG vaccine has long been recognized for reducing the risk to suffer from infectious diseases unrelated to its target disease, tuberculosis. Evid…
Despite significant progress in reaching some milestones of the United Nations Sustainable Development Goals, neonatal and early infant morbidity and…
The gut microbiome is a well-recognized modulator of host immunity, and its compositions differ between geographically separated human populations. S…
Vaccination remains one of the most effective means of reducing the burden of infectious diseases globally. Improving our understanding of the molecu…
Conventional vaccine design has been based on trial-and-error approaches, which have been generally successful. However, there have been some major f…
In both high- and low-income countries, HIV-negative children born to HIV-positive mothers (HIV exposed, uninfected [HEU]) are more susceptible to se…
The textbook view of vaccination is that it functions to induce immune memory of the specific pathogen components of the vaccine, leading to a quanti…
Baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination respo…
We describe here the effects of treatment with interferon-α2b in a cohort of confirmed COVID-19 cases in Wuhan, China