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P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophagesThe P2X7R is highly expressed on the macrophage cell surface, and activation of infected cells by extracellular ATP has been shown to kill intracellular bacte
Research
Level of purposeful hand function as a marker of clinical severity in Rett syndromeWe investigated relationships between hand function and genotype and aspects of phenotype in Rett syndrome
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Evaluation of impact of 23 valent pneumococcal polysaccharide vaccine following 7 valent pneumococcal conjugate vaccine in Australian Indigenous children.Background: High incidence and serotype diversity of invasive pneumococcal disease (IPD) in Indigenous children in remote Australia led to rapid introduction of
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The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1)While it is known that the anti-inflammatory effects of interleukin (IL)-4 require new protein synthesis, the exact mechanisms by which IL-4 suppresses the prod
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Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort studyPerioperative respiratory adverse events in children are one of the major causes of morbidity and mortality during paediatric anaesthesia.
Research
Smoking status, mental disorders and emotional and behavioural problems in young peopleTo examine the relationship between smoking behaviour, mental disorders and emotional and behavioural problems in a nationally representative sample of young pe
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Deep inspiration and airway physiology: human, canine, porcine, or bovine?Deep inspiration and airway physiology: human, canine, porcine, or bovine?
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Type 2 Diabetes in Indigenous Australian childrenRates of type 2 diabetes are higher among Indigenous than non-Indigenous Australian children and adolescents.
The Rio Tinto Children's Diabetes Centre is a research centre that aims to improve the lives of children and young adults living with diabetes by bringing together research, education and clinical care.