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Research

What is the evidence for managing tone in young children with, or at risk of developing, cerebral palsy: a systematic review

To conduct a systematic review of the evidence for the management of tone in infants 0-24 months of age, with or at risk of developing cerebral palsy.

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Neuroanatomical Predictors of Functional Outcome in Individuals at Ultra-High Risk for Psychosis

The poorest functional outcomes have the lowest grey matter densities at identification as ultra-high risk for psychosis

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Sialic acid-to-urea ratio as a measure of airway surface hydration

We explored a robust method to estimate mucus hydration using sialic acid as a marker for mucin content.

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Investigating facial phenotype in autism spectrum conditions: The importance of a hypothesis driven approach

The identification of differences in the facial phenotype of individuals with ASC may contribute to efforts to promote early identification of the condition and help elucidate etiological pathways.

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Use of the ketogenic diet to manage refractory epilepsy in CDKL5 disorder

In view of its side effect profile, ketogenic diet (KD) administration should be supervised by a pediatric neurologist and specialist dietician.

Research

Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 study

The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average.

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Latent Class Analysis of Neurodevelopmental Deficit After Exposure to Anesthesia in Early Childhood

Some studies suggest an association between early exposure to anesthesia, surgery and long term developmental deficit, clinical phenotype of children is unknown

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Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

In December 2016, a panel of experts was convened by the International Scientific Association for Probiotics an Prebiotics to review the scope of prebiotic.

Research

Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder

There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder have an atypical pattern of crying