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Long-term exposure of mice to 890 ppm atmospheric CO2 alters growth trajectories and elicits hyperactive behaviours in young adulthoodAtmospheric carbon dioxide (CO2) levels are currently at 418 parts per million (ppm), and by 2100 may exceed 900 ppm. The biological effects of lifetime exposure to CO2 at these levels is unknown. Previously we have shown that mouse lung function is altered by long-term exposure to 890 ppm CO2. Here, we assess the broader systemic physiological responses to this exposure.
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In Vitro primary human airway epithelial whole exhaust exposureThe method outlined in this article is a customization of the whole exhaust exposure method generated by Mullins et al. (2016) using reprogrammed primary human airway epithelial cells as described by Martinovich et al. (2017). It has been used successfully to generate recently published data (Landwehr et al. 2021). The goal was to generate an exhaust exposure model where exhaust is collected from a modern engine, real-world exhaust concentrations are used and relevant tissues exposed to assess the effects of multiple biodiesel exposures.
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Editorial overview: The physiology of the diseased lungAlexander Larcombe BScEnv (Hons) PhD Honorary Research Fellow Honorary Research Fellow Associate Professor Alexander Larcombe began work at The Kids
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Confounding effects of gavage in mice: Impaired respiratory structure and functionIt is therefore clear that gavage can have significant impacts on experimental animals in terms of their stress response and overall morbidity and mortality
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National committee shares collective voice for researchEver wondered what a national committee does? Who can be a member and what they do?
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Diabetes researcher Dr Aveni Haynes awarded prestigious international fellowshipCongratulations to Principal Research Fellow Dr Aveni Haynes from The Kids Research Institute Australia and the University of Western Australia.
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Avid cyclist Theo Grant completes Everesting eventWA teenager Theo Grant has been living with type 1 diabetes since he was two-years-old, but the condition hasn't stopped him from setting big goals
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Diabetes in Schools milestoneThe Diabetes in Schools team at the Perth Children’s Hospital have just reached a huge milestone – 1000 school visits!
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Steering Committee MemberSteering Committee Member Is your child currently using the Diabetes Service at PCH? Are you interested in better use of diabetes data to improve
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Type 1 diabetes National Screening Pilot launches in WADid you know that 9 out of 10 children diagnosed with type 1 diabetes have no family history of the condition?
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COVID Update August 2022We have been advised by the Department of Infectious Diseases at Perth Children's Hospital and the Wesfarmers Centre of Vaccines and Infectious Diseases at The Kids Research Institute Australia that COVID-19 vaccinations are now available for young children aged 6 months to 4 years with type 1 diabetes.
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Covid Vaccination StatementRe: Recommendations from the Diabetes and Endocrinology Department at Perth Children’s Hospital and the Children’s Diabetes Centre at The Kids Research Institute Australia regarding COVID-19 vaccination for children with diabetes
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Medtronic 780G Exciting News!Medtronic have announced the release of the new Medtronic pump – the 780G with Smartguard features.