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Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemiaRearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and re
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Tumor Antigen Cross-Presentation and the Dendritic Cell: Where it All Begins?Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that are critical for the generation of effective cytotoxic T lymphocyte (CTL) responses;
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Fetal androgen exposure and pragmatic language ability of girls in middle childhoodPrenatal exposure to testosterone has been shown to affect fetal brain maturation as well as postnatal cognition and behavior in animal studies.
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No role for neutrophil elastase in influenza-induced cellular recruitment, cytokine production or airway hyperresponsiveness in micePrevious studies have suggested that in vitro modulation of neutrophil chemokines and inflammatory cytokines by neutrophil elastase (NE) does not translate to t
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Stability of interleukin 8 and neutrophil elastase in bronchoalveolar lavage fluid following long-term storageInterleukin-8 (IL-8) and neutrophil elastase (NE) are commonly measured markers of inflammation in bronchoalveolar lavage (BAL) fluid from patients with cystic
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Fetal androgen exposure and pragmatic language ability of girls in middle childhood:This is the first prospective study to identify an association between early life testosterone exposure and pragmatic language difficulties in girls
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Parental occupational exposure to potential endocrine disrupting chemicals and risk of hypospadias in infantsRates and types of hospitalisations for children who have subsequent contact with the child protection system: a population based case-control study
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Contribution of an intrinsic lag of continuous glucose monitoring systems to differences in measured and actual glucose concentrationsCurrent continuous glucose monitoring (CGM) systems measure glucose levels in the interstitial fluid to estimate blood glucose concentration.
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Structural and IgE binding analyses of recombinant Der p 2 expressed from the hosts Escherichia coli and Pichia pastorisThe house dust mite allergen Der p 2 is one of the most important indoor allergens associated with allergic disease.
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Lung homing T-cell generation is dependent on strength and timing of antigen delivery to lymph nodesInhaled allergens are known for their immediate and ongoing effects in the respiratory tract (RT).