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Reports and Findings

Next-generation Malaria Vaccines Stakeholder Engagement Meetings held at ASTMH

At the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Meetings in 2024 and 2025, our team convened stakeholder engagement sessions on next-generation malaria vaccines.

Modelling to support next-generation malaria vaccines

In this project, we will generate model-driven insights to accelerate and optimise how next-generation malaria vaccines and monoclonal antibodies are developed, evaluated, and deployed, across different age groups, use-cases, and transmission settin…

Reimagining OpenMalaria and Supporting Novel Tools

This project consists of two linked research programs, working to support malaria control and elimination using OpenMalaria: our in-house, open-source, malaria simulation tool.

The Flourishing Child: Study Protocol for an Acceptability and Feasibility Trial of a Digital Early Childhood Flourishing Intervention

Globally, rates of children with physical and mental health problems are increasing. Health issues in early childhood often persist into adulthood, highlighting the need to ensure children are supported to flourish from the start of life.

Cardiovascular outcomes for Australian women with rheumatic heart disease during pregnancy: A retrospective linked data analysis, 2002–2017

Rheumatic heart disease (RHD) is the acquired autoimmune heart valve damage resulting from untreated infection with the Streptococcus pyogenes bacterium, which affects people experiencing socioeconomic disadvantage globally. This study measured RHD-…

An Exploratory Study of Serum 25-Hydroxyvitamin D Concentration and Psychological Distress Among Aboriginal and Torres Strait Islander Peoples in Australia

The colonisation of Australia around 250 years ago left a significant enduring impact on the mental health of Aboriginal and Torres Strait Islander peoples. Vitamin D may play a role in modulating mental health as its receptors are present in the br…

Aboriginal Consensus on Principles, Priorities and Actions for Culturally Safe Mental Health Services: A Delphi Study

Culturally unsafe mental health services contribute to persistent inequities for Aboriginal and Torres Strait Islander peoples, yet existing cultural safety frameworks lack clear, prioritised, community-endorsed implementation guidance. This study a…

CXCR3 is associated with T-cell-induced heart damage in acute rheumatic fever

The pathogenesis of acute rheumatic fever (ARF) is poorly understood, limiting the development of immune-modulating therapies to treat disease and prevent progressive heart damage. Here, participants with definite ARF were compared to other severe a…

Group mindful self-compassion training to improve mental health outcomes for gender and sexually diverse young adults

This study investigated the effects of Mindful Self-Compassion (MSC) training on the mental health of gender and sexually diverse young adults (aged 18–25 years) in Australia. A single-blind randomized controlled trial was conducted in 2020–2022 com…

Determinants of secondary prophylaxis for childhood rheumatic heart disease in Ethiopia: A qualitative study of children and caregivers

Rheumatic heart disease remains a major public health challenge in Ethiopia, particularly among children. Monthly intramuscular benzathine penicillin G is the cornerstone of secondary prophylaxis, yet adherence and delivery are suboptimal. This stud…