Reports and Findings
Research
Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsinPresent a valuable resource for drug discovery and have identified ROM as a promising therapeutic for MLL-rearranged iALL
Research
Epigenetic modifications: Mechanisms of disease and biomarkers of food allergyThe rise in IgE-mediated food allergy in recent times is the likely result of gene-environment interactions mediated via epigenetic pathways.
Research
Soft neurological signs and prenatal alcohol exposure: A population-based study in remote AustraliaSoft neurological signs were more common in children with prenatal alcohol exposure or FASD, consistent with the known neurotoxic effect of PAE
Research
Rhinovirus-induced asthma exacerbations and risk populationsAsthma exacerbations are heterogeneous conditions that involve the complex interplay between environmental exposures and innate and adaptive immune function
Research
How well can poor child development be predicted from early life characteristics? A whole-of-population data linkage studyA targeted program would have the potential to prevent one-quarter of the cases of being vulnerable on two or more AEDC domains at age five
Research
Interobserver reliability of the Australian Spasticity Assessment Scale (ASAS)The Australian Spasticity Assessment Scale complies with the definition of spasticity and is clinically feasible in paediatric settings
Research
Human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine for the prevention of cervical cancer and HPV-related diseasesHPV-16/18 AS04-adjuvanted vaccine reduces HPV-16/18 infection and associated cervical endpoints in women regardless of age, location, or sexual experience
Research
Longitudinal research: Applications for the design, conduct and dissemination of early childhood researchThe conduct of longitudinal research in early childhood is the focus of this chapter
Research
The relationship between Bordetella pertussis genotype and clinical severity in Australian children with pertussisIn children, we found no relationship between Prn status and markers of severe pertussis
Research
Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in AustraliaChinese immigrants living in Australia for a longer period of time have increased overall genome methylation and decreased overall gene expression