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The SYMBA Study - Promoting Gut Health (SYMBiosis) for Allergy prevention

Debbie Susan Desiree Palmer Prescott Silva BSc BND PhD MBBS BMedSci PhD FRACP MBBS, FRACP, MPH, PhD Head, Nutrition in Early Life Honorary Research

Healthway supports innovative mental health, physical activity research at The Kids

The Kids Research Institute Australia and The University of Western Australia researchers have been awarded more than $1 million in funding from Healthway, for projects to improve the mental health of LGBTQA+ young people, encourage early physical activity in childcare centres and create healthier local environme

Papers & Publications

Publications, papers and findings coming out of ORIGINS and its sub-projects

Breastfeeding

Convenient, readily available and helping create a close and loving bond between baby and mother, breastfeeding is highly regarded for optimising infant health and preventing chronic disease in adulthood.

Modelling to support malaria strategy and portfolio management

This project forms a program of modelling to inform the Gate's Foundation’s malaria product development portfolio, otherwise known as the Integrated Portfolio Management (IPM) project.

Next-generation Malaria Vaccines Stakeholder Engagement Meetings held at ASTMH

At the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Meetings in 2024 and 2025, our team convened stakeholder engagement sessions on next-generation malaria vaccines.

Strep A modelling: OpenStrepA

Strep A causes a huge global burden of disease, from sore throats to rheumatic heart disease. Our team is developing a computer simulation model, OpenStrepA, to help researchers tackle this disease.

A Single-Armed Pilot Study to Evaluate a Psychosocial Intervention for Young People Who Have Experienced a Burn Injury: The Wellbeing Study

Children with serious burns often suffer psychosocial consequences. This study evaluated the pilot of a 6-session psychoeducational intervention newly designed to support the wellbeing of children who experienced burns.

The development, content and response process validation of a caregiver-reported severity measure for CDKL5 deficiency disorder

CDKL5 Deficiency Disorder (CDD) is a severe X-linked developmental and epileptic encephalopathy. Existing developmental outcome measures have floor effects and cannot capture incremental changes in symptoms. We modified the caregiver portion of a CDD clinical severity assessment (CCSA) and assessed content and response-process validity. 

Study protocol for controlled human infection for penicillin G against Streptococcus pyogenes: a double-blinded, placebo-controlled, randomised trial to determine the minimum concentration required to prevent experimental pharyngitis (the CHIPS trial)

Regular intramuscular benzathine penicillin G injections have been the cornerstone of rheumatic heart disease (RHD) secondary prophylaxis since the 1950s. As the pharmacological correlate of protection remains unknown, it is difficult to recommend changes to this established regimen. Determining the minimum effective penicillin exposure required to prevent Streptococcus pyogenes infection will accelerate development of new long-acting penicillins for RHD prevention as well as inform opportunities to improve existing regimens. The CHIPS trial will address this knowledge gap by directly testing protection afforded by different steady state plasma concentrations of penicillin in an established model of experimental human S. pyogenes pharyngitis.