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Research

A molecular dynamics study of C1r and C1s dimers: Implications for the structure of the C1 complex

Complement is an important part of the immune system. It is initiated through three different pathways known as the classical, lectin, and alternative pathway.

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Father mental health during the early parenting period: results of an Australian population based longitudinal study

The primary objective of this study was to report on the occurrence of mental health difficulties for a large national sample of Australian fathers of children.

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Patterns of attendance of children under 12 years at school dental service in Western Australia

The aim of this study was to investigate patterns of attendance at School Dental Service and reasons for attendance for children in the Perth Metropolitan area.

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Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood

The effect of breast-feeding on the development of allergic disease is uncertain

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Reference values for spirometry: The way forward for our patients

Few clinical respiratory laboratories have assessed the impact of changing reference equations on the interpretation of spirometric outcomes.

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How many doses make a difference? An analysis of secondary prevention of rheumatic fever and rheumatic heart disease

increased adherence to penicillin prophylaxis is associated with reduced acute rheumatic fever recurrence and a likely reduction in mortality

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Transcriptional blood signatures for active and amphotericin B treated visceral leishmaniasis in India

Amphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani

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Optimising the use of linked administrative data for infectious diseases research in Australia

Increased collaboration and engagement across all sectors can optimise the use of linked data to help reduce the burden of infectious diseases

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Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP

Our results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells